abstract：BACKGROUND:The nematode Strongyloides stercoralis has a very particular autoinfection life-cycle which leads to chronic infections remaining undetected for decades. However, hyperinfection can occur in patients receiving immunotherapy resulting in high mortality rates. The main objective of this study was to assess the...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Valerio L,Roure S,Fernández-Rivas G,Basile L,Martínez-Cuevas O,Ballesteros ÁL,Ramos X,Sabrià M,North Metropolitan Working Group on Imported Diseases.

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Ultrasound utilization studies in the developing world are important to support appropriate use. METHODS:A prospective, cross-sectional study in the medical wards at Queen Elizabeth Central Hospital, Blantyre, Malawi, was performed which aimed to assess referrals, reports and usefulness of scans to develop ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Brindle HE,Allain TJ,Kampondeni S,Kayange N,Faragher B,Bates I,Joekes E

更新日期：2013-07-01 00:00:00

abstract：:This paper provides an overview of the methods in which geographic information systems (GIS) and remote sensing (RS) technology have been used to visualise and analyse data related to vectorborne diseases (VBD) in West Africa and to discuss the potential for these approaches to be routinely included in future studies ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Ratmanov P,Mediannikov O,Raoult D

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVES:Mid-upper arm circumference (MUAC) and weight-for-height Z-score (WHZ) identify different populations of children with severe acute malnutrition (SAM) with only some degree of overlap. In an urban slum in Bangladesh, we conducted a prospective cohort study on children assessed as being severely malnourished ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Ali E,Zachariah R,Shams Z,Vernaeve L,Alders P,Salio F,Manzi M,Allaouna M,Draguez B,Delchevalerie P,Harries AD

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Two long sewerage canals in the city of Kolkata, India were heavily infested with larvae, pupae and egg rafts of the mosquito Culex quinquefasciatus. Although the burden of bancroftian filariasis and other diseases transmitted by C. quinquefasciatus in the city is practically zero, the night-biting mosquitoe...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Biswas D,Mandal B,Biswas B,Banerjee A,Mukherjee TK

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:The state of Rio de Janeiro has been important since 1986 as a portal for the introduction of dengue virus (DENV) into Brazil and dissemination of the virus throughout the country. This study describes an active surveillance of DENV in the state of Rio de Janeiro from 2004 to 2008. METHOD:A total of 14 408 ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Macedo GA,de Araújo JM,Schatzmayr HG,Costa FA,de Filippis AM,Santos FB,Nogueira RM

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:In the last decade immigration to Europe has increased, with Africa being the source of a large number of immigrants. In addition to infections, this group has other less known health problems, such as erythrocyte abnormalities. METHODS:The objectives of this study were: the systematic evaluation of red cel...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： de-la-Iglesia-Iñigo S,Carranza-Rodriguez C,Ropero-Gradilla P,González-Fernandez FA,Molero-Labarta T,Hemmersbach-Miller M,Pérez-Arellano JL

更新日期：2013-02-01 00:00:00

abstract：:Previous studies have shown that apoptosis-like features are observed in Blastocystis spp., an intestinal protozoan parasite, when exposed to the cytotoxic drug metronidazole (MTZ). This study reports that among the four subtypes of Blastocystis spp. investigated for rate of apoptosis when treated with MTZ, subtype 3 ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Dhurga DB,Suresh KG,Tan TC,Chandramathi S

更新日期：2012-12-01 00:00:00

abstract：:Residents of a slum community of Dhaka city, Bangladesh were tested by serological and faecal examination for evidence of Strongyloides stercoralis infection. In stool specimens from a total of 147 participants Strongyloides larvae were found in 34 (23.1%) by Harada-Mori culture, 15 (10.2%) by agar plate culture (APC)...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Sultana Y,Gilbert GL,Ahmed BN,Lee R

更新日期：2012-12-01 00:00:00

abstract：:Simple pit latrines often represent the cheapest form of sanitation for poor communities. However, simple latrines lack a concrete slab and are therefore classified as an unimproved form of sanitation. This study collected soil samples in simple pit latrines and analysed them for the presence of helminth eggs; 71% of ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Baker SM,Ensink JH

更新日期：2012-11-01 00:00:00

abstract：:Severe febrile illness is a major cause of adult hospital admission in Africa. Studies of non-malarial fever come largely from children or from high HIV prevalence settings. This prospective study of adult admissions with severe febrile illness in a malaria-endemic area with moderate/low HIV prevalence investigated ad...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Nadjm B,Mtove G,Amos B,Walker NF,Diefendal H,Reyburn H,Whitty CJ

更新日期：2012-11-01 00:00:00

abstract：:The genetic polymorphism of Leishmania (Viannia) braziliensis detected in cases of mucosal leishmaniasis (ML) from HIV-infected and non HIV-infected patients was evaluated. Nine samples from three HIV-infected patients and five samples from five non HIV-infected patients were analysed by polymerase chain reaction (PCR...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： de Oliveira FS,Valete-Rosalino CM,Schubach Ade O,Madeira Mde F,Pacheco Rda S

更新日期：2012-11-01 00:00:00

abstract：:Pyomyositis remains poorly documented in tropical Latin America. We therefore performed a retrospective review of cases admitted to a hospital in the upper Negro river basin during 2002-2006. Seasonality was assessed by the cosinor model and independent predictors of outcome were identified by logistic regression. Det...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Borges AH,Faragher B,Lalloo DG

更新日期：2012-09-01 00:00:00

abstract：:A case-control study was carried out in Kassala and Medani Maternity Hospitals in Sudan to investigate acute-phase proteins [haptoglobin, C-reactive protein (CRP), ferritin and albumin] in three groups of pregnant women (32 in each arm) comprising those with severe Plasmodium falciparum malaria or uncomplicated P. fal...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Saad AA,Mohamed OE,Ali AA,Bashir AM,Ali NI,Elbashir MI,Adam I

更新日期：2012-09-01 00:00:00

abstract：:Prevalence of skin and eye disorders in African onchocerciasis (river blindness) is well documented. However, less is known about their joint occurrence. Information on concurrence may improve our understanding of disease pathogenesis and is required to estimate the disease burden of onchocerciasis. We analysed data f...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Coffeng LE,Fobi G,Ozoh G,Bissek AC,Nlatté BO,Enyong P,Olinga JM,Zouré HG,Habbema JD,Stolk WA,de Vlas SJ,Boussinesq M,Noma M

更新日期：2012-04-01 00:00:00

abstract：:The diagnostic performance of procalcitonin and neopterin as markers for bacterial and viral causes of fever was evaluated in a cohort of 69 febrile travellers with known etiological agents. Our aim was to establish a decision rule to minimize empirical antibiotic treatment. Compared with C-reactive protein (CRP) and ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： te Witt R,Hassing RJ,Petit PP,van Belkum A,van Genderen PJ

更新日期：2012-04-01 00:00:00

abstract：:Helicobacter pylori epidemiology in sub-Saharan Africa, particularly among children, has been little investigated. A secondary endpoint of our study was to examine for associations between the seroprevalence of H. pylori and the incidence of malaria. We explored H. pylori prevalence by measuring serum IgG antibodies t...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Gupta V,Perez-Perez GI,Dorsey G,Rosenthal PJ,Blaser MJ

更新日期：2012-01-01 00:00:00

abstract：:Tuberculosis (TB) remains a major cause of mortality despite availability of effective chemotherapy. This study was performed to identify contributing factors for poor outcome during anti-tuberculosis treatment at a teaching hospital chest clinic. Medical records of registered patients treated for TB between 1 January...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Burton NT,Forson A,Lurie MN,Kudzawu S,Kwarteng E,Kwara A

更新日期：2011-12-01 00:00:00

abstract：:Clostridium difficile is the most commonly identified bacterial cause of nosocomial and HIV-related diarrhea. In many developing countries, antibiotic access is unregulated. Nigeria has the third highest HIV burden worldwide. Due to perceptions of low prevalence and resource incapacity, patients with diarrhea are not ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Onwueme K,Fadairo Y,Idoko L,Onuh J,Alao O,Agaba P,Lawson L,Ukomadu C,Idoko J

更新日期：2011-11-01 00:00:00

abstract：:The safety and tolerability of primaquine (PQ) administered as a short higher-dose (30mg twice daily for 7 days) regimen in 203 Australian Defence Force personnel was evaluated in an open-label presumptive anti-relapse therapy study. No clinically significant differences were measured in the subjects' haematological a...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Ebringer A,Heathcote G,Baker J,Waller M,Shanks GD,Edstein MD

更新日期：2011-10-01 00:00:00

abstract：:Correct diagnosis of parasitic infections is essential for the treatment of individuals avoiding indiscriminate use of anthelmintics which increases drug resistance. In a comparative study between the spontaneous sedimentation technique and Paratest(®), 140 stool samples were analyzed for the detection of parasites. T...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Brandelli CL,Cargnin ST,Willers DM,Oliveira KR,Tasca T

更新日期：2011-10-01 00:00:00

abstract：:The optimum treatment for louse-borne relapsing fever (LBRF) has not been fully established. Eliminating spirochetes is often associated with the potentially lethal Jarisch-Herxheimer reaction (JHR). The objective of this meta-analysis was to review the evidence supporting the use of antibiotics usually employed for t...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Guerrier G,Doherty T

更新日期：2011-09-01 00:00:00

abstract：:Evaluating the performance of well child clinics on adherence to recommended perinatal hepatitis B prevention programmes as well as assessing the outcome of infants living with hepatitis B surface antigen (HBsAg)-positive parents is important. A retrospective study was performed of 336 babies who had at least one HBsA...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Polat S,Camurdan AD,Aksakal N,Agladioglu S,Beyazova U,Sahin F,Atak A,Er A

更新日期：2011-04-01 00:00:00

abstract：:Hepatitis E virus (HEV) infection is an important cause of acute viral hepatitis in tropical and sub-tropical regions that occurs both as epidemic episodes and sporadic cases. The aim of this investigation was to estimate the prevalence of total immunoglobulin (Ig) anti-hepatitis E virus (anti-HEV) and the risk factor...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Villalba MC,Guan M,Pérez A,Corredor MB,Frometa SS,Moreno AG,Hu WP,Howard T,Lay LA,Anderson D

更新日期：2010-12-01 00:00:00

abstract：:Our study aimed to determine anti-HBc total (IgG+IgM) seroprevalence in the adult population aged ≥ 15 and to compare the cost of testing for HBsAg and anti-HBs in only anti-HBc positive+ subpopulation to that in the whole population for HBV screening. The study involved a face-to-face survey and peripheral blood samp...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Ozkan S,Atak A,Bozdayi G,Turkcuoglu S,Maral I

更新日期：2010-12-01 00:00:00

abstract：:There is an urgent need for a non-toxic and low-cost treatment for cutaneous leishmaniasis. We synthesised and tested in vivo an amphotericin B-poly(methacrylic acid) drug (AmB-PMA) that had previously shown in-vitro activity against Leishmania major and L. donovani parasites. Efficacy was determined using L. major fo...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Corware KD,Rogers M,Teo I,Müller I,Shaunak S

更新日期：2010-11-01 00:00:00

abstract：:This prospective study was carried out from October 2003 to December 2005 and involved a cohort of 946 individuals of both genders, aged 1-89 years, from an endemic area for American visceral leishmaniasis (AVL), in Pará State, Brazil. The aim of the study was to analyze the dynamics of the clinical and immunological ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Silveira FT,Lainson R,Crescente JA,de Souza AA,Campos MB,Gomes CM,Laurenti MD,Corbett CE

更新日期：2010-08-01 00:00:00

abstract：:Lymphatic filariasis (LF) caused by Wuchereria bancrofti is widely prevalent in tropical and subtropical countries. Night blood film examination is most commonly used for diagnosis of filariasis but is cumbersome and labour intensive. In order to develop an indirect ELISA-based immunodiagnostic test, the importance of...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Singh A,Kamal S,Rathaur S

更新日期：2010-08-01 00:00:00

abstract：:The objectives of this study were to establish the prevalence of Chagas' disease among HIV seropositive patients and to define the clinical profile of co-infected cases. Cross-sectional study: the prevalence of co-infected subjects was 1.3% and there was no significant difference between co-infected and non co-infecte...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Almeida EA,Lima JN,Lages-Silva E,Guariento ME,Aoki FH,Torres-Morales AE,Pedro RJ

更新日期：2010-07-01 00:00:00

abstract：:The demographics, epidemiology, first aid, clinical management, treatment and outcome of snake bites causing no significant signs of systemic envenoming were documented in Chittagong Medical College Hospital, Bangladesh, between May 1999 and October 2002. Among 884 patients admitted, 350 were systemically envenomed an...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Harris JB,Faiz MA,Rahman MR,Jalil MM,Ahsan MF,Theakston RD,Warrell DA,Kuch U

更新日期：2010-05-01 00:00:00

abstract：:The precise function of Plasmodium falciparum histidine-rich protein II (HRPII) is not known, but in vitro studies have indicated its immunomodulatory function. The host immune response to HRPII was measured and compared with the response to P. falciparum merozoite surface protein 1 (MSP1) in four groups of study subj...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Das P,Grewal JS,Chauhan VS

更新日期：2010-05-01 00:00:00

abstract：:The natural host of Plasmodium knowlesi is the kra monkey, Macaca fascicularis, but this parasite, initially mistaken for P. malariae, is now infecting humans in some areas of Southeast Asia. Here we present data from experiments performed in the 1970s in which sera from a few naive M. fascicularis, taken in the cours...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Butcher GA,Mitchell GH,Cohen S

更新日期：2010-01-01 00:00:00

abstract：:Sleeping arrangements under long-lasting impregnated nets (LLIN) were recorded in 2467 households during the low malaria transmission season (May-June 2007) and the same families were followed up during the high malaria transmission season (December 2007-January 2008) in two malaria-endemic areas of Sri Lanka. Approxi...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Fernando SD,Abeyasinghe RR,Galappaththy GN,Gunawardena N,Ranasinghe AC,Rajapaksa LC

更新日期：2009-12-01 00:00:00

abstract：:The objectives of this study were to identify individuals with symptomatic and/or asymptomatic infection due to Leishmania (L.) infantum chagasi; to study the two types of infection, both clinically and immunologically, and to determine the prevalence rate of infection at the beginning of the study. This was a cross-s...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Crescente JA,Silveira FT,Lainson R,Gomes CM,Laurenti MD,Corbett CE

更新日期：2009-12-01 00:00:00

abstract：:We previously standardized the direct agglutination test (DAT) to detect anti-Leishmania chagasi promastigote antibodies (DAT-LPC) with good sensitivity and specificity for diagnosing visceral leishmaniasis (VL). In this paper, we present a technical upgrade by introducing some modifications into the antigen preparati...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Oliveira E,Pedras MJ,de Assis IE,Rabello A

更新日期：2009-12-01 00:00:00

abstract：:Trachoma surveys were conducted at baseline in five districts of Amhara National Regional State, Ethiopia (7478 participants in 1096 households) and at 3-year evaluation (5762 participants in 1117 households). Uptake of SAFE was assessed with programme monitoring data and interviews, and children (1-6 years) were swab...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Ngondi J,Gebre T,Shargie EB,Adamu L,Ejigsemahu Y,Teferi T,Zerihun M,Ayele B,Cevallos V,King J,Emerson PM

更新日期：2009-10-01 00:00:00

abstract：:Schistosomiasis is a major parasitic infection of tropical areas. We present a 26-year-old male immigrant from Egypt with acute abdomen due to schistosomial infection, mimicking symptoms of acute appendicitis, with histopathological detection and representation of schistosomial eggs in the unusual area of the greater ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Konstantinidou E,Alexiou C,Demonakou M,Sakellaridis T,Fotopoulos A,Antsaklis G

更新日期：2009-10-01 00:00:00

abstract：:Lesions due to Mycobacterium ulcerans infection may have more synonyms and eponyms than any other disease. New diseases are named for the person who discovered them, from the place from which they were first described or some major clinical feature. 'Buruli ulcer', the name by which the disease is most frequently know...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Radford AJ

更新日期：2009-10-01 00:00:00

abstract：:We report two patients who presented with a long-lasting febrile illness associated with pancytopenia. Both of them had evidence of hypercellular marrow with haemophagocytosis. They were confirmed as having rickettsial infections by serology and had a rapid haematological recovery with anti-rickettsial antibiotics. We...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Premaratna R,Williams HS,Chandrasena TG,Rajapakse RP,Kularatna SA,de Silva HJ

更新日期：2009-09-01 00:00:00

abstract：:The aim of this work was to conduct an epidemiological and clinical review of 1126 cases of envenoming by spider recorded in the national notifiable diseases information system (SINAN) files of the Municipal Health Secretary of the Criciúma region, Santa Catarina State, Brazil from 1994 to 2006. This work presents a c...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Cristiano MP,Cardoso DC,Raymundo MS

更新日期：2009-09-01 00:00:00